The preparation of 1-(3,4-dimethoxyphenethyl amino)-3-(substituted phenoxy)-2-propanols.

摘要

There is disclosed a process for preparing a compound of the following general formula <CHEM> wherein Z is a lower (C1-4) alkoxy, chloro, cyano, hydroxyalkyl, aryl, m-lower (C1-4) alkyl, or o-vinylic; which process comprises (1) reacting a compound of the following general formula <CHEM> with beta-(3, 4-dimethoxyphenyl) ethylamine having the formula <CHEM> at a temperature of 20 C or less than 20 C m