摘要 |
<p>The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="23" wi="49" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein</p><p>Rx together with either Ry<Sub>1</Sub> or R<Sub>Y2</Sub> represent the moiety
<Chemistry id="chema02" num="0002"><Image id="ia02" he="15" wi="22" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></p><p>(the other Ry being hydrogen),
<UnorderedLists id="ula01" listStyle="none"><ListItem>n represents the number 1, 2 or 3,</ListItem><ListItem>R represents hydrogen or a (1-4 C)-alkyl group,</ListItem><ListItem>R<Sub>1</Sub> represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl and</ListItem><ListItem>R<Sub>2</Sub> is hydrogen, hydroxyl or (1-4 C)-alkyl, as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.</ListItem></UnorderedLists></p> |