发明名称 Cycloalkane-indene-carboximidamide derivatives.
摘要 <p>The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="23" wi="49" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein</p><p>Rx together with either Ry&lt;Sub&gt;1&lt;/Sub&gt; or R&lt;Sub&gt;Y2&lt;/Sub&gt; represent the moiety &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="15" wi="22" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;</p><p>(the other Ry being hydrogen), &lt;UnorderedLists id="ula01" listStyle="none"&gt;&lt;ListItem&gt;n represents the number 1, 2 or 3,&lt;/ListItem&gt;&lt;ListItem&gt;R represents hydrogen or a (1-4 C)-alkyl group,&lt;/ListItem&gt;&lt;ListItem&gt;R&lt;Sub&gt;1&lt;/Sub&gt; represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl and&lt;/ListItem&gt;&lt;ListItem&gt;R&lt;Sub&gt;2&lt;/Sub&gt; is hydrogen, hydroxyl or (1-4 C)-alkyl, as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.&lt;/ListItem&gt;&lt;/UnorderedLists&gt;</p>
申请公布号 EP0165628(A1) 申请公布日期 1985.12.27
申请号 EP19850200772 申请日期 1985.05.17
申请人 AKZO N.V. 发明人 BEETZ, TOM, DR.
分类号 A61K31/155;C07C;(IPC1-7):C07C123/00;C07C135/00 主分类号 A61K31/155
代理机构 代理人
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