摘要 |
<p>Compounds of formula I <CHEM> wherein X, Y, n, R1, R2, R3 may have the following meanings, in all the possible combinations: X and Y, which may be the same or different, represent H, CH3, C1-C6 alkyl groups, optionally substituted, aryl groups; n is 0, 1, 2; R1 represents Cl, F, Br, C1-C6 alkyl groups, aryl and alkylaryl groups optionally substituted; R2 and R3, which may be the same or different represent H, CH3, alkyl groups, cycloalkyl groups, aryl-alkyl groups containing heteroatoms, heterocyclic groups optionally benzocondensed; prepared from substituted amino-acetohydrazides and imidazo (2,1-b)-thiazole-5-carboxyaldehydes, have remarkable diuretic and antihypertensive activities.</p> |