| 摘要 |
PURPOSE:To deprotect selectively only a protecting group of acetal type, by heat-treating a compound containing a protecting group of acetal type and a protecting group of silyl ether type in the molecule. CONSTITUTION:A compound (e.g., 1-tetrahydropyranyloxy-10-t-butyldimethylsilyloxydecane, etc.) containing one or more protecting group of acetal type (e.g., tetrahydropyranyl group, etc.) and a protecting group of silyl ether type (e.g., t-butyldimethylsilyl group, etc. in the molecule is heated preferably in a solvent (e.g., toluene, etc.) at 100-250 deg.C, to give a compound (e.g., 1-t-butyldimethylsilyloxy-10-decanol, etc.) wherein the protecting group of acetal type is selectively deprotected. |
