发明名称 |
Cytotoxicity assays in cell culturing devices |
摘要 |
Methods and devices for assaying the sensitivity of of biopsied cells to therapeutic agents are disclosed. Cells are cultured in artificial organs and then contacted with a fluorogenic substrate such that living cells accumulate a characteristic amount of fluorescence. The agent is then introduced into the organ and changes in the fluorescence released by the cells serve as an indicator of the sensitivity of the cells to the agent.
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申请公布号 |
US4559299(A) |
申请公布日期 |
1985.12.17 |
申请号 |
US19830463669 |
申请日期 |
1983.02.04 |
申请人 |
BROWN UNIVERSITY RESEARCH FOUNDATION INC. |
发明人 |
ROTMAN, M. BORIS |
分类号 |
G01N33/52;C12M1/34;C12N5/00;C12N5/06;C12Q1/04;C12Q1/18;G01N21/76;G01N33/50;(IPC1-7):C12Q3/00;C12N5/02;C12M3/00;C12M1/00 |
主分类号 |
G01N33/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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