摘要 |
<p>The present invention is concerned with novel acylindole derivatives of the formula (I) and platelet-aggregation inhibiting agents containing them as an active ingredient. <IMAGE> (I) In the formula (I), either R1 and R2 is hydrogen, an alkyl group having 1 to 5 carbon atoms, an alkyl group substituted by at least one hydroxy group and having 1 to 5 carbon atoms, or a group of the formula <IMAGE> in which R3 is an alkyl group having 1 to 5 carbon atoms, and -OR2 is a substituent at the ortho or para position. The compounds of the invention are useful as preventive medicine or remedy for various diseases or symptoms caused by platelet-aggregation, as well as inhibitors of platelet-aggregation on vascular walls during or after an operation.</p> |