4-ARYL-2-AMINO-PYRIMIDINES OR 4-ARYL-2-AMINOALKYL-PYRIMIDINES AS JAK-2 MODULATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM,申请号WO2007US02515-传众专利搜索

发明名称	4-ARYL-2-AMINO-PYRIMIDINES OR 4-ARYL-2-AMINOALKYL-PYRIMIDINES AS JAK-2 MODULATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要	This invention relates to certain pyrimidine derivative inhibitors of JAK-2, having Formula (I): wherein D, E, L, Z, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>25</SUP>, and n1 are as defined in the specification, pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof.
申请公布号	WO2007089768(A3)	申请公布日期	2007.09.20
申请号	WO2007US02515	申请日期	2007.01.30
申请人	EXELIXIS, INC.;MANN, GRACE;AAY, NAING;ARCALAS, ARLYN;BROWN, S. DAVID;CHAN, WAI KI VICKY;CHEN, JEFF;DU, HONGWANG;EPSHTEYN, SERGEY;FORSYTH, TIMOTHY;GALAN, ADAM A.;HUYNH, TAI PHAT;IBRAHIM, MOHAMED ABDULKADER;JOHNSON, HENRY WILLIAM BEECROFT;KANE, BRIAN;KEARNEY, PATRICK;KIM, BYUNG GYU;KOLTUN, ELENA;LEAHY, JAMES WILLIAM;LEE, MATTHEW SANGYUP;LEWIS, GARY L.;MEYR, LISA E.;NOGUCHI, ROBIN TAMMIE;PACK, MICHAEL;RIDGWAY, BRIAN HUGH;SHI, XIAN;WOOLFREY, JOHN;ZHOU, PEIWEN	发明人	MANN, GRACE;AAY, NAING;ARCALAS, ARLYN;BROWN, S. DAVID;CHAN, WAI KI VICKY;CHEN, JEFF;DU, HONGWANG;EPSHTEYN, SERGEY;FORSYTH, TIMOTHY;GALAN, ADAM A.;HUYNH, TAI PHAT;IBRAHIM, MOHAMED ABDULKADER;JOHNSON, HENRY WILLIAM BEECROFT;KANE, BRIAN;KEARNEY, PATRICK;KIM, BYUNG GYU;KOLTUN, ELENA;LEAHY, JAMES WILLIAM;LEE, MATTHEW SANGYUP;LEWIS, GARY L.;MEYR, LISA E.;NOGUCHI, ROBIN TAMMIE;PACK, MICHAEL;RIDGWAY, BRIAN HUGH;SHI, XIAN;WOOLFREY, JOHN;ZHOU, PEIWEN
分类号	C07D239/42;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D405/04;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/04;C07D413/12;C07D417/12;C07D453/02;C07D487/04	主分类号	C07D239/42
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