IMPLANT TISSUE

摘要

A collagenous fibrous tissue preparation of human or animal origin which is suitable for homo-or hetero transplantation as a permanent implant. The fibrous tissue preparation is preferably in sheet form and is prepared by a process which results in the fibrous tissue being substantially free of non-fibrous tissue proteins, glycoproteins, cellular elements, lipids and lipid residues. This process involves treatment of the fibrous tissue with a polyisocyanate which unlike earlier processes using, for example, dialdehyde treatment agents, provides a fibrous tissue preparation which is non-cytotoxic and is stable to endogenous proteolytic enzymes. The preparation and use of the fibrous tissue is also described.