发明名称 |
P-alkyl or cycloalkyl phenoxy alkanols and alkanol esters and use for the treatment of allergic conditions. |
摘要 |
Compounds of the formula
<CHEM>
and the pharmaceutically acceptable esters thereof wherein R is alkyl (1-6C) or cycloalkyl (1-6) optionally fused to the benzene of th ecompound of formula I at positions 3 and 4; and Z is a straight chain alkylene (1-15C) optionally substituted by one or two lower alkyl (1-3C); with the proviso that if the compound of formula I is unesterified, Z cannot be unsubstituted prpylene are disclosed. These compounds, as well as unesterified forms wherein Z is unsubstituted propylene are useful in preventing allergic reactions in humans.
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申请公布号 |
EP0162975(A1) |
申请公布日期 |
1985.12.04 |
申请号 |
EP19840303577 |
申请日期 |
1984.05.25 |
申请人 |
PHARMACO DEVELOPMENT PARTNERS |
发明人 |
BERGER, FRANK M.;DEGRAW, JOSEPH I., JR.;JOHNSON, HOWARD L. |
分类号 |
C07C43/205;C07C43/215;C07C43/23;C07C51/367;C07D213/80;(IPC1-7):C07C43/23;C07C125/04;C07C69/96;C07C69/78;C07C69/157;A61K31/21;A61K31/455;A61K31/085 |
主分类号 |
C07C43/205 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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