发明名称 P-alkyl or cycloalkyl phenoxy alkanols and alkanol esters and use for the treatment of allergic conditions.
摘要 Compounds of the formula <CHEM> and the pharmaceutically acceptable esters thereof wherein R is alkyl (1-6C) or cycloalkyl (1-6) optionally fused to the benzene of th ecompound of formula I at positions 3 and 4; and Z is a straight chain alkylene (1-15C) optionally substituted by one or two lower alkyl (1-3C); with the proviso that if the compound of formula I is unesterified, Z cannot be unsubstituted prpylene are disclosed. These compounds, as well as unesterified forms wherein Z is unsubstituted propylene are useful in preventing allergic reactions in humans.
申请公布号 EP0162975(A1) 申请公布日期 1985.12.04
申请号 EP19840303577 申请日期 1984.05.25
申请人 PHARMACO DEVELOPMENT PARTNERS 发明人 BERGER, FRANK M.;DEGRAW, JOSEPH I., JR.;JOHNSON, HOWARD L.
分类号 C07C43/205;C07C43/215;C07C43/23;C07C51/367;C07D213/80;(IPC1-7):C07C43/23;C07C125/04;C07C69/96;C07C69/78;C07C69/157;A61K31/21;A61K31/455;A61K31/085 主分类号 C07C43/205
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