BASICALLY SUBSTITUTED 4-PHENYL-4,5,6,7-TETRAHYDRO- THIENO[2,3-C]PYRIDINES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

There are described 4-phenyl-4,5,6,7-tetrahydro-thieno¢2,3-c!pyridines of formula I and the acid addition salts thereof, processes for their preparation them and pharmaceutical compositions containing them. In the new compounds of formula < IMG > (I) R1 represents an amino, acetylamino, hydroxymethyl, methoxymethyl, or < IMG > , group wherein R5 and R6, which may be the same or different, each represent a hydrogen atom alkyl group with 1 to 4 carbon atoms or, R5 and R6 together with the nitrogen atom to which they are attached represent a 5-, 6- or 7-membered ring, any 6-membered ring optionally containing an oxygen atom; R2 and R3, which may be the same or different, represent a hydrogen, fluorine, chlorine or bromine atom or a trifluoromethyl, hydroxy, methoxy, methyl or ethyl group; and R4 represents a straight- or branched-chained alkyl group with 1 to 3 carbon atoms. The new compounds may be used as active substances for compositions for the treatment of depressive states of various origins.