Ethanolamine compounds.

摘要

The invention provides compounds of the general formula (I) <CHEM> wherein Ar represents a phenyl group optionally substituted by one or two substituents selected from halogen atoms, or C1-3 alkyl or C1-3 alkoxy groups, or by an alkylenedioxy group of formula -O(CH2)pO- where p is 1 or 2; R1 and R2 each represents a hydrogen atom or a C1-3 alkyl group with the proviso that the sum total of carbon atoms in R1 and R2 is not more than 4; m is an integer from 2 to 8 and n is an integer from 1 to 7 with the proviso that the sum total of m + n is 4 to 12; Q represents a group of formula <CHEM> where R<3> represents a hydrogen atom or a C1-3 alkyl group, R<a> represents: <CHEM> and R<b> represents: <CHEM> where R<4> represents a straight or branched C2-3 alkylene chain; and physiologically acceptable salts and solvates thereof. The compounds of formula (I) have a selective stimulant action at beta 2-adrenoreceptors and are useful, in particular in the treatment of diseases associated with reversible airways obstruction such as asthma and chronic bronchitis.