发明名称 | Methods for reducing global chronic inflammation and the presence of melanoma | ||
摘要 | This document relates to methods and materials involved in treating cancer (e.g., melanoma). For example, methods and materials involved in using an anti-chronic inflammation treatment (e.g., chemotherapy) in combination with a cancer treatment agent (e.g., a cancer vaccine) to treat cancer are provided. | ||
申请公布号 | US9387244(B2) | 申请公布日期 | 2016.07.12 |
申请号 | US201314051849 | 申请日期 | 2013.10.11 |
申请人 | Mayo Foundation for Medical Education and Research | 发明人 | Markovic Svetomir N. |
分类号 | A61K39/00;A61K38/00;A61K51/10;A61K39/395;A61K31/337;A61K31/4188;A61K31/555;A61K31/675;A61K45/06;A61K31/56 | 主分类号 | A61K39/00 |
代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
主权项 | 1. A method for treating a mammal having stage IV melanoma, said method comprising: (a) administering to said mammal an anti-chronic inflammation treatment, (b) detecting, in a blood sample obtained from said mammal, a reduction in IL-4, IL-5, IL-10, and IL-13 level following said step (a), wherein said reduction is indicative of reduced global chronic inflammation, and (c) after detecting said reduced global chronic inflammation, administering to said mammal a cancer treatment agent under conditions wherein the presence of said melanoma is reduced, wherein said cancer treatment agent is paclitaxel, carboplatin, bevacizumab, anti-CTLA-4, a MART-1 cancer vaccine, a gp 100 cancer vaccine, a survivin cancer vaccine, or a tyrosinase cancer vaccine. | ||
地址 | Roschester MN US |