发明名称 Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
摘要 The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like.
申请公布号 US9416161(B2) 申请公布日期 2016.08.16
申请号 US201414163755 申请日期 2014.01.24
申请人 TRUSTEES OF TUFTS COLLEGE 发明人 Herman Ira M.
分类号 A61K38/18;C07K14/475;C07H21/04;C07K14/435;C07K7/08;C07K14/47;C07K7/06;C12N15/113;A61K38/00 主分类号 A61K38/18
代理机构 Loeb & Loeb LLP 代理人 Loeb & Loeb LLP
主权项 1. A peptide comprising an amino acid sequence that is not less than 95% identical to the amino acid sequence of SEQ ID NO: 3.
地址 Medford MA US