| 摘要 |
A wound dressing is provided that adheres or bonds directly to tissue when activated by energy without the use of an adhesive layer. The wound dressing may be applied to a mucosal surface or to wounds due to trauma or surgery to protect the wound, promote healing, and reduce pain. The wound dressing comprises crosslinked gelatin with additives, such as a plasticizer, a surfactant and/or cysteine. Pharmaceutical agents to treat the wound may also be added. Applying energy, such as plasma, ultrasound, radio frequency, light or heat energy, causes the wound dressing to adhere or bond to an underlying wound or tissue and may also increase the flexibility or elongation of the wound dressing. The wound dressing may be generally planar, convex or concave to match the shape of the wound to be treated and may have through holes and/or a coating on an external surface of the film. |
