发明名称 Methylene:amino:thiazolyl:methyl:thio-propylidene sulphamide
摘要 <p>1-Amino 3-(((2-(diaminomethylene amino) 4-thiazolyl) methyl) thio) propylidene sulphamide of formula (I) is made by (a) reacting ((2-(diaminoethylene amino) 4-thiazolyl) methyl) isothiourea of formula (II) with a cpd. of formula (III) in presence of potassium or sodium hydroxide in presence of inert organic solvent such as methanol, ethanol, acetone, etc. at 0-25 deg.C to obtain (I), and (b) isolating the prod. by conventional methods. W is a reactive ester gp.</p>
申请公布号 ES8506664(A1) 申请公布日期 1985.11.16
申请号 ES20030005368 申请日期 1984.10.17
申请人 INKE, S.A. 发明人
分类号 A61K31/425;C07D277/38;(IPC1-7):C07D277/38 主分类号 A61K31/425
代理机构 代理人
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