| 摘要 |
PURPOSE:To produce the titled compound useful as an intermediate of dyes, pharmaceuticals, etc., in high yield and purity, without using a catalytic poison, by the catalytic hydrogenation of a nitrobenzene compound in a specific mixed solvent in the presence of a noble metal catalyst. CONSTITUTION:The objective compound can be produced by the catalytic hydrogenation of the nitrobenzene compound of formula (R is H, halogen, lower alkyl or lower alkoxy, when R is other than H, it is substituted to o- or m- position of nitro group; n is 1-2) in a mixed solvent consisting of a lower aliphatic alcohol, sulfuric acid and an aliphatic carboxylic acid or its aqueous solution, in the presence of a catalyst such as platinum, palladium, etc. supported by activated carbon, at 30-60 deg.C. The amounts of the alcohol and sulfuric acid are 20-100mol and 1-10mol per 1mol of the nitrobenzene compound of formula, and the content of the lower aliphatic carboxylic acid in the mixed solvent is preferably 1.5-10wt%. |
