发明名称 |
AZEPINO (1 2-A) PYRIMIDINE DERIVATIVES |
摘要 |
The invention relates to new azepino[1,2-a]pyrimidine derivatives-of the general formula <IMAGE> I wherein p=1, 2 and acid addition salts thereof which can be prepared by (a) reacting a compound of the formula <IMAGE> II with a compound of the general formula <IMAGE> III wherein p is as defined above and R7 is alkoxycarbonyl containing 2 to 5 carbon atoms or carboxamido or (b) reacting a compound of the general formula <IMAGE> IV wherein R8 is alkyl containing 1 to 4 carbon atoms with a compound of the general formula <IMAGE> V wherein R7 is as defined above and if desired converting a compound of the general formula I to acid addition salt thereof or setting it free from the salt thereof. The new compounds show bronchodilatory activity. |
申请公布号 |
GB2131018(B) |
申请公布日期 |
1985.11.13 |
申请号 |
GB19830029344 |
申请日期 |
1983.11.03 |
申请人 |
* CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT |
发明人 |
ISTVAN * HERMECZ;LELLE * VASVARI;AGNES * HORVATH;SANDOR * VIRAG;TIBOR * BREINING;JOZSEF * KOKOSI |
分类号 |
A61K31/519;A61K31/55;A61P11/08;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K31/519 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|