发明名称 PROCEDIMIENTO PARA LA OBTENCION DE LA N-((5-TRIFLUOROMETIL)-6METOXI-1-NAFTALELIN)TIOXOMETIL)-N-METILGLICINA
摘要 <p>The process comprises reaction of 2 (((5-(trifluoromethyl) 6-methoxy-1-naphthalenyl) thioxomethyl)-thio) acetic acid with N-methyl glycine in a basic medium and solvent. The prod., N-((5-trifluoromethyl) 6-methoxy-1-naphthalenyl) thioxomethyl) N-methyl glycine, is sepd. in the usual way. - The reaction is partic. effective in water with or without methanol admixture and at 20-30 deg.C. The basis medium is e.g. sodium carbonate in a 2:1 molar ratio relative to the N-methyl glycine, used e.g. in 5-10% excess relative to the stoichiometric reaction 1:1 molar ratio.</p>
申请公布号 ES538855(D0) 申请公布日期 1985.11.01
申请号 ES19550005388 申请日期 1984.12.20
申请人 INKE SA 发明人
分类号 A61K31/095;A61K31/195;(IPC1-7):C07C149/43 主分类号 A61K31/095
代理机构 代理人
主权项
地址