| 摘要 |
PURPOSE:The titled remedy showing anti-psoriasis activity equal to or more than triamcinolone, capable of being administered continuously, containing a 1-hydroxy-2-pyridone well-known as a dandruff inhibitor or its salt as an active ingredient. CONSTITUTION:A remedy containing a compound shown by the formula (R1 is H, 1-23C alkyl, 2-23C alkenyl, etc.; R2 and R4 are H, 1-9C alkyl, etc.; R3 is H, 1-23C alkyl, etc.) or its salt as an active ingredient. Especially compounds such as 1-hydroxy-4-methyl-6-undecyl-2-pyridone, 1-hydroxy-4-methyl-6-tridecyl- 2-pyridone, etc. having 4-19C alkyl or 3-8C cycloalkyl as the 6-position substituent group are preferable compounds. Zinc 1-hydroxy-2-pyrithione of a dandruff inhibitor shows no anti-psoriasis activity, and there is no relationship between a remedy for psoriasis, etc. and a dandruff inhibitor.
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