发明名称 OXAZOLEACETIC ACID DERIVATIVES
摘要 <p>of the disclosure: A compound of the formula: < IMG > wherein R1 is (A) a group of the formula, < IMG > wherein R4 is H, a halogen or trifluoromethyl group, or (B) a group of the formula, < IMG > wherein n is O or an interger of 1 to 3; R5 is H or an alkyl group of 1 to 6 carbon atoms; respective R6 and R7 are an alkyl group of 1 to 6 carbon atoms, an alkenyl group of 2 to 6 carbon atoms, a cycloalkyl group of 3 to 7 carbon atoms, or a cycloalkenyl group of 5 to 7 carbon atoms; R6 and R7 may be combined with the neighbouring carbon atom to represent a cycloalkyl group of 3 to 7 carbon atoms; a cycloalkenyl group of 5 to 7 carbon atoms, a bicycloalkyl group of 7 to 10 carbon atoms, or a bicycloalkyl group of 7 to 10 carbon atoms; R2 is an alkyl group of 1 to 6 carbon atoms; and R3 is H, an alkyl group of 1 to 6 carbon atoms or an aralkyl group, or a pharmaceutically acceptable salt thereof. The compound has hypoglycemic, glucose tolerance improving and insulin sensitivity potentiating activities.</p>
申请公布号 CA1195986(A) 申请公布日期 1985.10.29
申请号 CA19830429900 申请日期 1983.06.07
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 MEGURO, KANJI;FUJITA, TAKESHI
分类号 A61K31/42;A61K31/421;A61P3/08;A61P3/10;C07D263/32;C07D263/40;(IPC1-7):C07D263/32 主分类号 A61K31/42
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