摘要 |
<p>of the disclosure: A compound of the formula: < IMG > wherein R1 is (A) a group of the formula, < IMG > wherein R4 is H, a halogen or trifluoromethyl group, or (B) a group of the formula, < IMG > wherein n is O or an interger of 1 to 3; R5 is H or an alkyl group of 1 to 6 carbon atoms; respective R6 and R7 are an alkyl group of 1 to 6 carbon atoms, an alkenyl group of 2 to 6 carbon atoms, a cycloalkyl group of 3 to 7 carbon atoms, or a cycloalkenyl group of 5 to 7 carbon atoms; R6 and R7 may be combined with the neighbouring carbon atom to represent a cycloalkyl group of 3 to 7 carbon atoms; a cycloalkenyl group of 5 to 7 carbon atoms, a bicycloalkyl group of 7 to 10 carbon atoms, or a bicycloalkyl group of 7 to 10 carbon atoms; R2 is an alkyl group of 1 to 6 carbon atoms; and R3 is H, an alkyl group of 1 to 6 carbon atoms or an aralkyl group, or a pharmaceutically acceptable salt thereof. The compound has hypoglycemic, glucose tolerance improving and insulin sensitivity potentiating activities.</p> |