发明名称 Antihypertensive amides
摘要 Compounds of the structure: <IMAGE> wherein R1, R2, R3, R4, R5, and R6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, n is an integer from 0 to 4 inclusive, M is heterocyclic or heterocyclic alkyl, Y is hydroxy, alkoxy, amino, or substituted amino, amino-alkanoyl, aryloxy, aminoalkoxy, or hydroxyalkoxy, and R7 is hydrogen, alkanoyl, carboxylalkanoyl, hydroxyalkanoyl, amino-alkanoyl, cyano, amidino, carbalkoxy, <IMAGE> wherein Z is hydrogen, alkyl, hydroxyalkyl, aminoalkyl or the radical <IMAGE> wherein R1, R2, R3, R4, R5, R6, n, M and Y are as described above; and where Y is hydroxy their nontoxic, pharmaceutically acceptable alkali metal, alkaline earth metal, and amine salts.
申请公布号 US4548928(A) 申请公布日期 1985.10.22
申请号 US19840672651 申请日期 1984.11.19
申请人 USV PHARMACEUTICAL CO. 发明人 SUH, JOHN T.;SKILES, JERRY W.;WILLIAMS, BRUCE E.;SCHWAB, ALFRED
分类号 A61K31/535;C07D207/08;C07D211/26;C07D213/40;C07D213/75;C07D217/22;C07D219/14;C07D235/30;C07D239/42;C07D277/46;C07D307/52;C07D307/66;C07D307/82;C07D309/14;C07D317/66;C07D319/18;C07D333/20;C07D333/36;C07D333/48;(IPC1-7):C07D265/32;C07D265/30 主分类号 A61K31/535
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