发明名称 |
Eburnane oxime ethers |
摘要 |
The invention relates to optically active or racemic eburnane-oxime ethers of the formulae (Ia) and/or <IMAGE> (Ia) <IMAGE> (Ib) wherein R represents an alkyl group having 1 or 2 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms, and the configuration of the hydrogen in the 3-position and the R2 group is alpha , alpha and/or beta , beta or alpha , beta and/or beta , alpha and acid addition salts thereof. The new compounds show valuable pharmaceutical activities, thus are potent CNS-tranquillants, smooth muscle relaxants, sedatives and hypnotic agents, and can therefore be employed as active ingredients of pharmaceutical compositions, which are also within the scope of the present invention.
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申请公布号 |
US4549020(A) |
申请公布日期 |
1985.10.22 |
申请号 |
US19830508437 |
申请日期 |
1983.06.27 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT. |
发明人 |
SZANTAY, CSABA;SZABO , LAJOS;KALAUS, GYORGY;SAPI, JANOS;ZAJER NEE BALAZS, MARIA;KISS, BELA;EZER, ELEMER;KARPATI, EGON;SZPORNY, LASZLO |
分类号 |
A61K31/435;A61P25/02;A61P25/20;C07D461/00;(IPC1-7):C07D461/00 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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