发明名称 Hypotensive benzoxathiole pyrrolidines
摘要 Compounds of the formula <IMAGE> and the pharmaceutically acceptable, nontoxic, acid addition salts thereof, wherein R1 and R2 are each independently -H, lower alkyl, or cycloalkyl, with the proviso that R1 and R2 cannot both be -H or cycloalkyl at the same time; R1 and R2 taken together are cycloalkyl of 4-7 carbons; n is 0 or 1; X is (CH2)2, CH=CH, or C 3BOND C; Y is independently selected from the group of -H, -Fl, -Br, -Cl, lower alkyl, and -OR3; wherein R3 is -H or lower alkyl; and a is 1 or 2, or two Y's taken together are -OCH2O-; are useful as regulators of the cardiovascular system, particularly as hypotensive agents.
申请公布号 US4548951(A) 申请公布日期 1985.10.22
申请号 US19830487335 申请日期 1983.04.21
申请人 SYNTEX (U.S.A.) INC. 发明人 MUCHOWSKI, JOSEPH M.;ACKRELL, JACK
分类号 C07D295/108;C07D317/54;C07D317/58;C07D327/04;C07D411/06;(IPC1-7):C07D411/06;A61K31/39 主分类号 C07D295/108
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