摘要 |
Compounds of the formula <IMAGE> and the pharmaceutically acceptable, nontoxic, acid addition salts thereof, wherein R1 and R2 are each independently -H, lower alkyl, or cycloalkyl, with the proviso that R1 and R2 cannot both be -H or cycloalkyl at the same time; R1 and R2 taken together are cycloalkyl of 4-7 carbons; n is 0 or 1; X is (CH2)2, CH=CH, or C 3BOND C; Y is independently selected from the group of -H, -Fl, -Br, -Cl, lower alkyl, and -OR3; wherein R3 is -H or lower alkyl; and a is 1 or 2, or two Y's taken together are -OCH2O-; are useful as regulators of the cardiovascular system, particularly as hypotensive agents.
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