| 摘要 |
Pyrrolidine, piperidine and homopiperidinecarboxamide and thiocarboxamide compounds of the formula: <CHEM> wherein X is -S-, -S(O)- or -S(O)2-; A is a loweralkalene chain and A<1> and A<2> are alkalene chains when p and d are one; R, R<1> and R<2> are hydrogen, loweralkyl, phenyl cycloalkyl or phenylalkyl and R<1> and R<2> may form a heterocyclic residue with the adjacent nitrogen atom; Q is a selected aromatic radical, and the pharmaceutically acceptable acid addition salts are useful as cardiac antiarrhythmia agents. Chemical intermediates, unsubstituted on pyrrolidine, piperidine and homopiperidine nitrogen but with the -(A<2>)p-X-(A<2>)d-Q side chain are also disclosed. |
