| 摘要 |
Compounds of the structure <IMAGE> and pharmaceutically acceptable salts thereof wherein: R1 is H, alkyl, alkoxy, carboxyl, alkylcarboxy, acylamino, dialkyl amino, trihalomethyl, halogen, nitro, hydroxy or cyano; X is in the 5, 6 or 7 position and is O(CH2)n, N(CH2)n-R3, S(CH2)n or (CH2)n; Y is O(CH2)n, S(CH2)n, N(CH2)n-R3 where R3 is H, alkyl or (CH2)n; R2 is monosubstituted or independently disubstituted H, hydroxy, alkyl, halogen, nitro, alkoxy, carboxyl, alkylcarboxy, trihalomethyl, cyano, trifluoromethyl, dialkylamino or acylamino; Z is O, S or (NR3)2 where R3 is H, alkyl or aryl; and n is 0 to 10 inclusive useful in the treatment of ischemic heart disease and hypertriglyceridemia.
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