| 摘要 |
PURPOSE:To identify effectively a BCG vaccine-sensitized living body and a human type tubercle bacillus-sensitized living body by using the D material derived from BCG bacilli as a tuberculin antigen. CONSTITUTION:A D material which is the novel and powerful tuberculin antigen derived from tubercle bacilli is isolated in early time and is verified later that the D material obtd. from the BCG bacilli in particular is the tuberculin antigen extremely powerful as compared with refined tuberculin (PPD) in a BCG vaccine-sensitized living body. On the other hand, it is found that said material exhibits extremly weak activity only as compared to PPD in a human type tubercle bacillus-sensitized living body, unlike the BCG vaccine-sensitized living body. Such characteristic is utilized for the diagnozing agent of this invention in which the D material derived from the BCG bacilli is used as an effective component to induce the specific reaction with the BCG vaccine-sensitized living body. The effective identification of the BCG vaccine-sensitized living body and the human type tubercle bacillus-sensitized living body is thus made possible. |
