NYA MONOKLONALA ANTIKROPPAR OCH HYBRIDOMACELLER, FOERFARANDE FOER FRAMSTAELLNING AV DESAMMA SAMT DERAS ANVAENDNING.

摘要

The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and structurally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.