COMPOSITION OF MATTER FOR TOPICAL APPLICATION COMPRISING A BIO-AFFECTING AGENT AND N,N-DIETHYL-M-TOLUAMIDE

摘要

Greatly enhanced delivery of a wide variety of bio-affecting agents is provided by formulations for topical application comprising at least one bio-affecting agent and N,N-diethyl-m-toluamide, optionally further comprising a non-toxic topical carrier. N,N-Diethyl-m-toluamide (DEET) acts as a unique transport agent which delivers the active agent across the stratum corneum to the target area. Cosmetic and therapeutic dermatological agents as well as systemically effective theraoeutic agents can be formulated with DEET and effectively delivered through the skin to the desired site, i.e. to the underlying tissues of the epidermis and dermis or to the general circulation.