发明名称 SYNTHESIS OF RADIOACTIVE COMPOUND USING NUCLEUS SEED WITH SHORT LIFE
摘要 PURPOSE:To obtain advantageously a radioactive compound using a nucleus seed with a short life, by presealing hermetically a given amount of an intermediate for the desired radioactive compound within a reactor, attaching the reactor to a device for synthesizing the radioactive compound in synthesis, carrying out synthetic reaction. CONSTITUTION:In synthesizing a radioactive compound using a nucleus seed with a short life, especially a radioactive drug such as <11>C-N-methylspiperone (dopamine receptor blocking agent) useful for diagnosis, examination, etc. with positron CT100, each of a given amount (necessary amount for one administration) of an intermediate (e.g., alkali salt of spiperone) for the compound together with an inert gas is presealed hermetically within the reactor 70, preserved, the reactor 70 is attached to the device 30 for synthesizing the radioactive compound in case of necessity, and the intermediate is reacted with <11>C-CH3I, etc., so that the desired compound is obtained stably and simply even if a radioactive substance is synthesized by introducing an unstable intermediate or an intermediate of complicated synthesis into a nucleus seed with a short life.
申请公布号 JPS60185730(A) 申请公布日期 1985.09.21
申请号 JP19840041648 申请日期 1984.03.05
申请人 SUMITOMO JUKIKAI KOGYO KK 发明人 TANAKA AKIRA
分类号 B01J19/00;A61K51/00;C07B31/00;C07B59/00;C07C67/00 主分类号 B01J19/00
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