摘要 |
PURPOSE:To prepare an D-alpha-amino acid, by treating a specific D-alpha-amino acid amide corresponding it with a culture solution of a specific bacterium belonging to the genus Achromobacter, Alcaligenes, or Kurthia, a live mold, or a treated material of it. CONSTITUTION:Achromobacter cycloclastes, Alcaligenes facealis, or Kurthia zophii having activity to hydrolyze D-alpha-amino acid is cultivated in an ordinary medium. When the culture solution, a live mold, or a treated material of it is treated with D-alpha-amino acid amide shown by the formula, a corresponding D- alpha-amino acid is prepared. In the formula, R is lower alkyl group, substituted lower alkyl group, phenyl group, substituted phenyl group, furyl group, pyridyl group, thiazolyl group, imidazolyl group, or indolyl group.
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