| 摘要 |
PURPOSE:To provide an eye drop containing pranoprofen and boric acid as active components, having strong anti-inflammatory activity, little irritation and no side effect, and applicable to herpetic ophthalmia. CONSTITUTION:The objective agent contains pranoprofen as an active anti- inflammatory component and boric acid as an isotonic agent. Pranoprofen (chemical name: alpha-methyl-5H[1]benzopyrano(2,3-b)pyridine-7-acetic acid) has anti- inflammatory, analgesic and antipyretic activities, and exhibits excellent effect to inflamation and pain. The standard concentration of pranoprofen is usually 0.01-0.5(w/v)%. The amount of boric acid is determined to give an osmotic pressure ratio of about 1, and is usually about 0.5-2(w/v)%. The pH of the eye drop is preferably about 6.5-8.5, especially about 7.5. |
