| 摘要 |
NEW MATERIAL:A pyrrole derivative shown by the formula I (A is 1-4C alkylene; B is O; one of l and n is 1, and the other is 0 or 1; m is 1-3, with the proviso that l+m+n=3 or 4). EXAMPLE:3-[2-(Pyrrolyl)ethyl]-2,4-oxazolidinedione. USE:A drug. having antiulcer action, useful as a remedy and preventive for gastric ulcer and duodenal ulcer of mammals including human. PREPARATION:A compound shown by the formula II(m' is 1 or 2) is reacted with a carbonyl compound such as N,N'-carbonylimidazole, etc., or the compound shown by the formula II is reacted with a halocarbonic acid ester such as methyl chlorocarbonate, etc. to form a compound shown by the formula III (R is 1-3C alkyl), which is heated in the presence of a basic substance such as CH3ONa, etc. to give a compound shown by the formula I wherein l and n are 1, and m is m'.
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