| 摘要 |
<p>NEW MATERIAL:The 25-hydroxyvitamin D3 derivative of formula I (R is H or OH-protecting group). USE:It has strong differentiation-inducing activity to cancer cells, and is useful as a remedy for cancer. PREPARATION:The compound of formula I wherein the 1a-OH group is protected with acyl is produced by treating 6,19-epidioxy-9,10-secocholesta-5(10),7-diene-3beta, 25-diol of formula II with an organic acid anhydride (e.g. acetic anhydride) and a base.</p> |
