METHOD AND COMPOSITION FOR BIOLOGICAL TESTING USING MAGNETIC SPHERES

摘要

A method for in vitro diagnosis of diseases or predisposition to certain diseases in animals, including humans, is disclosed, as is a diagnostic agent for use in this method. For the diagnosis, a suspension of viable cells from animals is contacted with magnetic spheres, which spheres are adsorbed on the cell walls or incorporated in the cells. After that, the magnetised viable cells are separated from the suspension by application of an external magnetic field. The viable cells are then analysed with regard to cell parameters, such as DNA repair proficiency and/or enzyme activity and/or immunological reactivity. The diagnostic agent consists of magnetic spheres comprising magnetic particles enclosed in a polymer matrix.