发明名称 5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use as anti-inflammatory agents
摘要 The present invention relates to novel 5-oxo-5H-[1]benzopyrano[2,3-b]pyridine derivatives useful for effective medicines for the treatment of various connective tissue diseases such as chronic rheumatoid arthritis and varieties of inflammatory diseases caused by immunoreaction, which have the following formula: <IMAGE> wherein R is the same or different and represents hydrogen, alkyl, alkoxy, nitro, hydroxyl, acyl, hydroxyalkyl, halogen with the proviso that m is 1,2 or 3, or a tetramethylene (-(CH2)4-) or butadienylene (-CH=CH-CH=CH-) group which, in conjunction with two adjacent carbon atoms on the ring, forms a six-membered ring with the proviso that m is 1; n is 1 or 2, or a physiologically acceptable salt or ester thereof.
申请公布号 US4539326(A) 申请公布日期 1985.09.03
申请号 US19830510723 申请日期 1983.07.05
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 NOHARA, AKIRA;KUZUNA, SEIJI
分类号 C07D491/04;C07D491/052;(IPC1-7):C07D491/00;C07D221/18;C07D471/00;A61K31/435 主分类号 C07D491/04
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