摘要 |
A collagen-coated vascular graft includes drug materials complexed with the collagen to be released slowly from the graft following implant, the graft incorporating a tubular porous synthetic vascular graft substrate having a coating of collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like. |