| 摘要 |
NEW MATERIAL:3-[3-[4-( 2-Methoxyphenyl )-1-piperazinyl]propyl]-2,4( 1H,3H)-quinazolidinedione of formula I and a salt thereof. USE:A remedy for diseases in circulatory organs, particularly diseases in cerebral circulatory organs. PREPARATION:For example, a compound of formula II obtained from 1-(2- methoxyphenyl)piperazine is reacted with trichloromethyl chloroformate in the presence of a base e.g. sodium hydrogencarbonate or triethylamine, or heated with urea in dimethylformamide to afford the aimed compound of formula I .
|
