| 摘要 |
Compounds of formula (I): <CHEM> or a salt thereof, wherein R<1> is hydrogen, halogen or trifluoromethyl, R<2> is hydrogen or halogen, R<3> is hydrogen or methyl, R<4> is hydrogen or methyl, R<5> is hydrogen or halogen, <CHEM> X is C3-20 straight or branched alkylene having at least two carbon atoms interposed between the oxygen and nitrogen atoms and having a hydroxyl substituent on a carbon atom not directly bonded to the oxygen or nitrogen atoms R<7> is hydrogen, C1-6 straight or branched alkyl, or optionally substituted benzyl, R<8> is hydrogen, C1-6 straight or branched alkyl or optionally substituted benzyl, or <CHEM> is a 5, 6 or 7 membered saturated heterocyclic group containing a total of one or two heteroatoms, the second heteroatom, when present, being selected from nitrogen, oxygen and sulphur, and n is 1 or 2, have antiobesity and antihyperglycaemic activity. |
