发明名称 MONOCLONAL ANTIBODY
摘要 <p>NEW MATERIAL:A monoclonal antibody having properties wherein it is reacted with a fraction containing D fraction and/or DD fraction but not with fibrinogen in a plasmin decomposition product of human fibrinogen or fibrin, having antigenic determinants recognizing each other. USE:For measuring a fibrinogen fibrin decomposition product (FDP for short). Capable of measuring FDP independently of an amount of fibrinogen. PREPARATION:First, a mouse is immunized against a D fraction or DD fraction of FDP obtained from human fibrinogen, an immunized antibody-forming cell of splenic cell of mouse is fused with a myeloma cell of mouse, to give a hybridoma of a monoclonal antibody-forming cell having specificity to FDP having D fraction and/or DD fraction. It is then cultivated in medium, to give a monoclonal antibody.</p>
申请公布号 JPS60166698(A) 申请公布日期 1985.08.29
申请号 JP19840020842 申请日期 1984.02.09
申请人 DAIICHI KAGAKU YAKUHIN KK 发明人 TERAMURA YASUO;NISHIJIMA YOSHIKAZU;MATSUMOTO TAKASHI;HIRATA MITSUYOSHI
分类号 G01N33/577;A61K39/00;A61K39/395;C07K14/00;C07K16/00;C12N5/10;C12N15/00;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/53 主分类号 G01N33/577
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