| 摘要 |
NEW MATERIAL:N-Trifluoromethyl-N-nitrosofluoromethanesulfonamide of the formula. USE:Useful as a reagent for introducing trifluoromethyl groups. The two trifluoromethyl groups remarkably increase the usefulness of the reagent as a trifluoromethylating agent. The decomposition products are wholly gases, and the separation of the trifluoromethyl compound can be very easily carried out. PREPARATION:Trifluoronitrosomethane is reacted with hydroxylamine, and the resultant product is then reacted with trifluoromethanesulfonyl fluoride in the presence of a base, e.g. NaOH, to afford the aimed compound of the formula. The reaction is preferably carried out in a solvent, e.g. DMF, at -100--10 deg.C.
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