| 发明名称 |
4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase |
| 摘要 |
Novel 4-substituted-3-hydroxy-3-pyrroline-2,5-diones are disclosed which inhibit glycolic acid oxidase and thus are useful in the treatment and prevention of calcium oxalate renal lithiasis.
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| 申请公布号 |
US4537902(A) |
申请公布日期 |
1985.08.27 |
| 申请号 |
US19790047412 |
申请日期 |
1979.06.11 |
| 申请人 |
MERCK & CO., INC.;MERCK SHARP & DOHME (I.A.) CORP. |
发明人 |
CRAGOE, JR., EDWARD J.;ROONEY, CLARENCE S.;WILLIAMS, HAYDN W. R. |
| 分类号 |
C07D207/44;C07D207/456;C07D403/10;(IPC1-7):C07D403/02;C07D207/40;A61K31/40 |
主分类号 |
C07D207/44 |
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