发明名称 |
Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
摘要 |
Topical pharmaceutical compositions comprising a pharmaceutically-active agent and a novel, penetration-enhancing vehicle or carrier are disclosed. The vehicle or carrier comprises a binary combination of N-(2-Hydroxyethyl) pyrrolidone and a "cell-envelope disordering compound". The compositions provide marked transepidermal and percutaneous delivery of the active selected. A method of treating certain pathologies and conditions responsive to the selected active, systemically or locally, is also disclosed.
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申请公布号 |
US4537776(A) |
申请公布日期 |
1985.08.27 |
申请号 |
US19830506273 |
申请日期 |
1983.06.21 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
COOPER, EUGENE R. |
分类号 |
A61K9/06;A61K9/70;A61K31/57;A61K45/06;A61K47/08;A61K47/22;(IPC1-7):A01N43/36;A61K31/40 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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