发明名称 7,8-Dihydroimidazo-(1,5-a)-Pyrazin-8-ones.
摘要 <p>Provided are compounds of the structure: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="32" wi="46" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;and pharmaceutically acceptable salts thereof, wherein R&lt;Sub&gt;1&lt;/Sub&gt;, R&lt;Sub&gt;3&lt;/Sub&gt;, R&lt;Sub&gt;5&lt;/Sub&gt; and R&lt;Sub&gt;6&lt;/Sub&gt; are independently H, alkyl, aralkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, formyl, carboxy, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, aminosulfonyl, carbamoyl or cycloalkyl; and &lt;UnorderedLists id="ula01" listStyle="none"&gt;&lt;ListItem&gt;R&lt;Sub&gt;7&lt;/Sub&gt; is H, alkyl, aryi, aralkyl, oxo, or alkanoyl;&lt;/ListItem&gt;&lt;/UnorderedLists&gt; wherein at least one of R&lt;Sub&gt;1&lt;/Sub&gt;, R&lt;Sub&gt;5&lt;/Sub&gt; or R&lt;Sub&gt;6&lt;/Sub&gt; is an aryl, heteroaryl, or heteroaryl substituted with H, alkyl, halo, amino, trifluoromethyl or cyano.</p>
申请公布号 EP0152077(A2) 申请公布日期 1985.08.21
申请号 EP19850101356 申请日期 1985.02.08
申请人 USV PHARMACEUTICAL CORPORATION 发明人 LEE, THOMAS DAW-YAUN
分类号 A61K31/495;A61P9/00;C07D233/92;C07D403/06;C07D487/04;(IPC1-7):C07D487/04 主分类号 A61K31/495
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