摘要 |
<p>Provided are compounds of the structure:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="32" wi="46" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and pharmaceutically acceptable salts thereof, wherein R<Sub>1</Sub>, R<Sub>3</Sub>, R<Sub>5</Sub> and R<Sub>6</Sub> are independently H, alkyl, aralkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, formyl, carboxy, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, aminosulfonyl, carbamoyl or cycloalkyl; and
<UnorderedLists id="ula01" listStyle="none"><ListItem>R<Sub>7</Sub> is H, alkyl, aryi, aralkyl, oxo, or alkanoyl;</ListItem></UnorderedLists>
wherein at least one of R<Sub>1</Sub>, R<Sub>5</Sub> or R<Sub>6</Sub> is an aryl, heteroaryl, or heteroaryl substituted with H, alkyl, halo, amino, trifluoromethyl or cyano.</p> |