摘要 |
<p>Novel 5-amino or substituted amino)-1,2,3-triazoles have the formula: <CHEM> in which R1 is phenyl or phenyl-(C1-3alkyl), either unsubstituted or having from one to five halogen, cyano, trifluoromethyl, C1-3 alkanoyl, nitro, C1-3alkyl, C1-3alkoxy, carboxy, alkoxycarbonyl, trifluoromethoxy, acetamido, C1-3alkylthio, C1-3alkylsulphinyl, C1-3alkylsulphonyl, trichlorovinyl, trifluoromethylthio, trifluoromethylsulphinyl and/or trifluoromethylsulphonyl substituents; or is phenacyl, pyridyl, pyridylmethyl naphthyl, naphthylmethyl, quinolyl or quinolylmethyl; R2 is amino, C1-3alkylamino, di(C1-3alkyl)amino, acetamido, acetamido, ureido, formamido, formimido or guanidino; and R3 is carbamoyl, cyano, carbazoyl, amidino or N-hydroxycarbamoyl. Such compounds are anticoccidial and are useful for controlling coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with their feed.</p> |