发明名称 |
Amino, cyano phenylthio or phenoxyl indole derivatives |
摘要 |
This invention relates to indole derivatives which have anti-cancer activity. According to the invention there is provided an indole derivative of the formula I: <IMAGE> I in which X is an oxygen or sulphur atom, Ra is a phenyl radical which is optionally substituted by one or two groups selected from halogen atoms and 1-6C alkyl, 1-6C alkoxy and trifluoromethyl radicals and Rb is a hydrogen atom or a 2-6C alkoxycarbonyl radical. Manufacturing processes and pharmaceutical compositions are also described.
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申请公布号 |
US4533672(A) |
申请公布日期 |
1985.08.06 |
申请号 |
US19830545010 |
申请日期 |
1983.10.24 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
EAKIN, MURDOCH A.;HAYTER, ANTHONY J.;FURR, BARRINGTON J. A. |
分类号 |
A61K31/40;A61K31/403;A61K31/404;A61P35/00;C07C67/00;C07C253/00;C07C255/42;C07C313/00;C07C323/62;C07D209/42;(IPC1-7):C07D209/42 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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