发明名称 Anti-depressant imidazoles
摘要 An anti-depressant imidazole compound of the formula: <IMAGE> wherein R1 is lower alkyl, R2 is hydrogen or lower alkyl, and R3, R4 and R5 are hydrogen, lower alkyl, trifluoromethyl, amino, mono- or di-lower alkylamino, heterocyclic amino, halogen or <IMAGE> (in which R6 is hydrogen, lower alkyl or lower alkylsulfonyl, A is carbonyl or sulfonyl, and R7 is lower alkyl, halogenated lower alkyl, mono- or di-lower alkylamino, mono- or di-lower alkylaminoalkyl, unsubstituted phenyl or phenyl having halogen, lower alkyl, lower alkoxy or trifluoromethyl, phenylamino or phenylamino having halogen, lower alkyl, lower alkoxy or trifluoromethyl); and their pharmaceutically acceptable acid addition salts. These compounds are useful as agents for treating depression and depressive states.
申请公布号 US4533669(A) 申请公布日期 1985.08.06
申请号 US19830469548 申请日期 1983.02.25
申请人 EISAI CO., LTD. 发明人 YAMANAKA, MOTOSUKE;SAITO, ISAO;YAMATSU, KIYOMI;FUJIMOTO, TAKAKO
分类号 A61K31/415;A61K31/445;C07D233/54;C07D233/56;C07D233/60;C07D233/61;C07D521/00;(IPC1-7):A61K31/415 主分类号 A61K31/415
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