发明名称 |
PROCESS FOR THE BIOTECHNOLOGICAL PREPARATION OF POLY-D-(-)-3-HYDROXYBUTYRIC ACID |
摘要 |
The present invention relates to a process for the biotechnological preparation of poly-D-(-)-3-hydroxybutyric acid (PHB) which comprises continuously culturing a microorganism that is a strain of Alcaligenes latus or a PHB-producing mutant thereof, in two separate successive fermentation stages with unrestricted supply of nutrients. The PHB-containing microorganism population cultured in the first stage with a dissolved oxygen content of 25 to 50% of the saturation value for air is then continuously transferred into a second fermentation stage in which the culture is continued at a dissolved oxygen content of 8-15% of the saturation value of air. The PHB is extracted in the usual manner from the biomass thereby obtained. |
申请公布号 |
ZA8409326(B) |
申请公布日期 |
1985.07.31 |
申请号 |
ZA19840009326 |
申请日期 |
1984.11.29 |
申请人 |
CHEMIE LINZ AKTIENGESELLSCHAFT |
发明人 |
ROBERT M. LAFFERTY;GERHART BRAUNEGG |
分类号 |
C12P7/44;C12P7/62;C12R1/05 |
主分类号 |
C12P7/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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