Assays for the determination of carcinogenicity

摘要

There is provided an assay for the determination of the carcinogenicity of chemical and physical agents, by exposing a selected line of tumor virus transformed cells to the agent to be tested and determining whether such exposure induces endogenous viral DNA replication in such cells, which induction is indicative of the carcinogenicity of the tested agent by in situ hybridization. There is provided a kit for carrying out such assay.