发明名称 |
AMINOCYCLOPENTANE ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION |
摘要 |
Compounds are described of the formulae < IMG > in which -COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans -CH=CH or -CH2CH2-, n is 1 or 2, Y is a saturated heterocyclic amino group having 5 - B ring members, and R2 is unsubstituted or substituted phenylalkyl, thienylalkyl, naphthylalkyl or cinnamyl, and their salts and solvates. These compounds inhabit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and antiasthmatic agents. |
申请公布号 |
CA1190926(A) |
申请公布日期 |
1985.07.23 |
申请号 |
CA19820411565 |
申请日期 |
1982.09.16 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
COLLINGTON, ERIC W.;HALLETT, PETER;WALLIS, CHRISTOPHER J.;WADSWORTH, ALAN;HAYES, NORMAN F.;BRADSHAW, JOHN;CARTER, MALCOLM |
分类号 |
A61K31/44;A61K31/445;C07C45/63;C07D213/65;C07D213/70;C07D295/14;C07D295/155;C07D307/33;C07D307/42;C07D307/46;C07D309/12;C07D311/00;C07D333/16 |
主分类号 |
A61K31/44 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|