| 摘要 |
Novel peptides represented by the following formula R1-A-B-C-D-Trp-Met-Y (1) wherein; R1 denotes pGlu, X-R2-CO-, X being carboxyl or amino and R2 being lower alkylene of 1-6 carbon atoms, or <IMAGE> A denotes Asp, Ala, or merely a chemical bond; B denotes Tyr(SO3H) or Phe(NHSO3H); C denotes Met or merely a chemical bond; D denotes Gly, D-Ala, or D-Trp; and Y denotes NH2, Asp-NH2, or Asp-Phe-NH2; with the proviso that Y is NH2 or Asp-NH2 when R1 is pGlu, HOOC-R2-CO-, or <IMAGE> B is Tyr(SO3H), C is Met, and D is Gly, and pharmacologically acceptable salts thereof.
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